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Atorvastatin generic pharmacy - marker- ing drug for the treatment of high cholesterol. They did not include one of the most commonly used statins—a statin that lowers cholesterol without lowering LDL cholesterol. These studies may have contained some bias because they were observational—they did not prove that the drug prevented these heart attacks and strokes. The findings were published online July 20 in JAMA Internal Medicine. "Anecdotal evidence is very important," says Thomas Hulmi of Scripps Research Institute, senior author of the paper. "But for benefit of prescribing decisions, large studies are needed that follow people for atorvastatin 10 mg cipla brand extended time periods, to track the overall health effect." The research comes as several companies are entering the market of lipid-lowering drugs for older people. The are considered safer in older people because of less severe heart symptoms. But there is still concern about potential problems with heart side effects, including stroke. The FDA plans to begin considering statin drug labels for older adults in October 2013. Currently, the U.S. Food and Drug Administration does not approve drugs for people age 65 and older. The agency also will not approve any drugs for people over age 70 or 65, until it has more evidence. The agency also approved first cardiovascular drug for high cholesterol. The statins and new statin drugs are all part of this class drugs known as statins. These were initially developed to lower high cholesterol—but because of the side effects they are known for, the FDA now approves them only for people with low and stable cholesterol. Statins are used to treat diseases such as cholesterol, high blood pressure, triglycerides and sugar, especially in healthy people. Doctors who prescribe these drugs for high cholesterol risk tend to prescribe them for many years before seeing if the drugs can prevent heart attacks and strokes. If the drugs do not improve heart patients' risk for attacks, they may consider switching to other lipid-lowering drugs. In a new trial that began late last year, the Scripps team decided to look at whether statin medications, which target cholesterol, reduce mortality in people at high risk for heart attack. The patients were at very high Buy liquid flagyl online risk for an acute myocardial infarction—or artery-clogging heart attack. About 5 percent of the subjects had a risk of having heart attack that was more than double of the remaining patients. A total of about 1 out 20 subjects had a heart attack during an average follow-up period of more than five years. The study enrolled more than 4,000 people in Denmark and Sweden who agreed to take part in long-term statin-drug studies. They had a higher chance of an acute myocardial infarction and died than did people not taking statins, the researchers found. Some of the patients in this study had heart attacks within six months of starting the statins. Others had heart attacks in their first few years taking the drugs or had no history of heart disease at all. People in the study with most severe heart disease—those three or more conditions—had about double the risk for death as people with the fewest symptoms of cardiac heart disease, the researchers found. The number of deaths in statin-drug group was about 11 percent higher than the number of deaths in statin-free group—and nearly 18 percent higher than the group who just took statins.

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